protein 1,344 words KG: FUSPROTEIN 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

FUS Protein

🔬 Protein Info
Gene SymbolFUS
Full NameFUS (Fused in Sarcoma)
AliasesFUSPROTEIN
Chromosome16p11.2.
Protein FamilyFUS/TLS family (FET family)
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular LocalizationNucleus, Cytoplasm
PathwaysBlood-Brain Barrier, Hippo Pathway, Oxidative Stress, Sod1, Tdp-43
UniProt IDSearch UniProt
GeneCardsFUS
Human Protein AtlasFUS
GeneFUS
PDB2LCW, 2YIO
Mol. Weight53 kDa
Associated DiseasesAD, ALI, ALS, AMI, Aging
Known Drugs/CompoundsRNA oligonucleotides, Rna Oligonucleotides, Antisense Oligonucleotide, ADUCANUMAB
InteractionsTARDBP, LC3, ACTB, G3BP1, BCL2, C9ORF72
SciDEX HypothesesASO-Mediated Exon Skipping to Restore FUS-TAZ Chap
KG Connections1482 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph