| Gene Symbol | GSDMD |
| Chromosome | 8p22 |
| Function | is a gene encoding a key executor of pyroptotic cell death |
| Primary Expression | hippocampus, temporal lobe, cortex, Substantia Nigra, Ca1 |
| Subcellular Localization | Cytoplasm |
| Molecular Weight | ~56 kDa (full-length) |
| Amino Acids | 484 aa |
| Pathways | Apoptosis, Ferroptosis, Inflammasome, Necroptosis, Oxidative Stress |
| UniProt ID | Q8NHS0 |
| GeneCards | GSDMD |
| Human Protein Atlas | GSDMD |
| Protein Name | GSDMD (Gasdermin D) |
| Protein Length | 484 amino acids |
| Strategy | Agent |
| GSDMD Inhibitors | Dimethyl fumarate |
| Associated Diseases | ALS, Alzheimer, Alzheimer's disease, Cancer, Cardiovascular |
| Known Drugs/Compounds | curcumin, natural products, Qingqi Liangying Formula, XHP, Pterostilbene |
| Interactions | SCD1, HMGCR, TNF, MLKL, ACSL4, MYD88 |
| KG Connections | 880 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |