| Gene Symbol | HMOX1 / HO-1 |
| Full Name | Heme Oxygenase 1 |
| Chromosome | 22q12 |
| Protein Type | Enzyme |
| Function | HMOX1 degrades heme to produce biliverdin (which is further converted to bilirubin), iron (which induces ferritin), and carbon monoxide (a signaling molecule). |
| Subcellular Localization | </strong></td><td>Microsomes, endoplasmic reticulum</td></tr> |
| Pathways | Autophagy, Chaperone, Immune Response, Mitophagy, Oxidative Stress |
| UniProt ID | P09601 |
| NCBI Gene ID | 3162 |
| Ensembl ID | ENSG00000101129 |
| OMIM | 141250 |
| Associated Diseases | ALS, Aging, Alzheimer, Atherosclerosis, Diabetes |
| Known Drugs/Compounds | L. reuteri-CMVs, rapamycin |
| Interactions | ALOX15, ALOX12, NFE2L2, FER, CD4, ALOX5 |
| KG Connections | 509 knowledge graph edges |
| Databases | GeneCardsHPASTRING |