concept

ALOXE3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ALOXE3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

60Connections

0Hypotheses

0Analyses

32Outgoing

28Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	ALOXE3
Key Genes/Proteins	ALOX15, ALOX12, AND, ALOX15B, ALOX, FER
Related Diseases	Als, Cancer, ALS

Pathway Diagram

graph TD
    ALOXE3["ALOXE3"]
    ALOXE3 -->|"interacts"| Als["Als"]
    ALOXE3 -->|"activates"| Cancer["Cancer"]
    ALOXE3 -->|"interacts"| ALS["ALS"]
    ALOXE3 -->|"contributes to"| ALOX12["ALOX12"]
    ALOXE3 -->|"contributes to"| AND["AND"]
    ALOXE3 -->|"contributes to"| ALOX15B["ALOX15B"]
    ALOXE3 -->|"contributes to"| ALOX["ALOX"]
    GENES["GENES"] -->|"contributes to"| ALOXE3
    ALOX12B["ALOX12B"] -->|"contributes to"| ALOXE3
    ALOX5["ALOX5"] -->|"contributes to"| ALOXE3
    ALOX15["ALOX15"] -->|"contributes to"| ALOXE3
    CANCER["CANCER"] -->|"activates"| ALOXE3

Outgoing (32)

Target	Relation	Type	Str
Lipoxygenases	associated_with	enzyme	0.90
ALOX15	associated_with	gene	0.85
lipoxygenase	associated_with	enzyme	0.80
Als	interacts_with	disease	0.65
Cancer	activates	disease	0.65
ALS	interacts_with	disease	0.65
ALOX12	contributes_to	gene	0.60
AND	contributes_to	gene	0.60
ALOX15B	contributes_to	gene	0.60
ALOX	contributes_to	gene	0.60
ALOX12	activates	gene	0.60
FER	activates	gene	0.60
AND	activates	gene	0.60
HMOX1	activates	gene	0.60
NFE2L2	activates	gene	0.60
CHAC1	activates	gene	0.60
Ferroptosis	activates	pathway	0.60
ALOX12B	contributes_to	gene	0.60
ALOX5	contributes_to	gene	0.60
GSH	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALOX5	activates	gene	0.60
ALOX15	contributes_to	gene	0.60
ALOX15	activates	gene	0.60
GENES	contributes_to	gene	0.60
SAT1	activates	gene	0.60
RNA	activates	gene	0.60
GENES	activates	gene	0.60
App	interacts_with	protein	0.60
Ras	activates	protein	0.60
ferroptosis	participates_in	pathway	0.60
ferroptosis	activates	process	0.60

Incoming (28)

Source	Relation	Type	Str
ALOX15	associated_with	gene	0.80
GENES	contributes_to	gene	0.60
ALOX12B	contributes_to	gene	0.60
ALOX5	contributes_to	gene	0.60
ALOX15	contributes_to	gene	0.60
GENES	activates	gene	0.60
ALOX5	activates	gene	0.60
ALOX15	activates	gene	0.60
CANCER	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALOX15B	contributes_to	gene	0.60
ALOX12	contributes_to	gene	0.60
AND	contributes_to	gene	0.60
HMOX1	activates	gene	0.60
RNA	activates	gene	0.60
NFE2L2	activates	gene	0.60
AND	activates	gene	0.60
GSH	activates	gene	0.60
CHAC1	activates	gene	0.60
ALOX	contributes_to	gene	0.60
SAT1	activates	gene	0.60
ALOX12	activates	gene	0.60
ALOX	implicated_in	gene	0.60
ALOX12	implicated_in	gene	0.60
ALOX12B	implicated_in	gene	0.60
ALOX15	implicated_in	gene	0.60
ALOX15B	implicated_in	gene	0.60
ALOX5	implicated_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found