protein 625 words KG: JAK3PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Janus Kinase 3

🔬 Protein Info
Gene SymbolJAK3PROTEIN
Chromosome19p13.11
Protein FamilyJanus kinase family
Protein TypeKinase
Functionis a Janus kinase family member.
Primary Expressionlymphoid cells and is essential for signaling by γc-family cytokines (IL-2, IL-4, IL-7, IL-9, IL-15, IL-21)
Subcellular LocalizationCytoplasm
Molecular Weight125 kDa
UniProt IDP52333
GeneCardsJAK3PROTEIN
Human Protein AtlasJAK3PROTEIN
Protein NameJanus Kinase 3
GeneJAK3
PDB IDs1JAK, 3LXK, 5WPX
Associated DiseasesInflammation, Ms, Neuroinflammation
InteractionsIRF1, GBM, STAT3, TYK2, JAK, PIK3C3
KG Connections79 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph