protein 1,091 words KG: LRP4PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

LRP4 Protein - LDL Receptor-Related Protein 4

🔬 Protein Info
Gene SymbolLRP4
AliasesPage for LRP4 Protein
Chromosome11p11.2
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight195 kDa
Amino Acids1725 aa
Exons33
PathwaysWnt signaling, Wnt
UniProt ID[Q9NPJ6](https://www.uniprot.org/uniprot/Q9NPJ6)
Ensembl IDENSG00000134538
GeneCardsLRP4
Human Protein AtlasLRP4
Associated DiseasesALS, Aging, Atherosclerosis, Cancer, Cardiovascular
InteractionsWNT, CANCER, PAH
KG Connections70 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (9)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses