protein 1,090 words KG: NAGLUPROTEIN 2026-03-28
kind:proteinsection:proteinsstate:publishedtopic:alzheimerstopic:parkinsons
Contents

NAGLU Protein (Alpha-N-Acetylglucosaminidase)

🔬 Protein Info
Gene SymbolNAGLU
Full NameAlpha-N-Acetylglucosaminidase
AliasesNAGLUPROTEIN
Protein TypeEnzyme
FunctionNAGLU encodes alpha-N-acetylglucosaminidase, a lysosomal enzyme that catalyzes the N-acetylglucosaminide hydrolysis in heparan sulfate glycosaminoglycans.
Subcellular Localization</strong></td><td>Lysosome</td></tr>
Molecular Weight73.9 kDa
Amino Acids739 aa
Ensembl IDENSG00000108784
GeneCardsNAGLU
Human Protein AtlasNAGLU
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsPLA2G4A, RBFOX3, RNA, ACTB, ATG12, ATG5
KG Connections20 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in