| Gene Symbol | NEFL |
| Full Name | Neurofilament Light Polypeptide |
| Chromosome | 8p21.2 |
| Protein Family | Intermediate filament family |
| Function | is a neuronal intermediate filament protein encoded by the NEFL gene on chromosome 8p21. |
| Primary Expression | CNS and PNS neurons (axons) |
| Subcellular Localization | Axon, neuronal cytoplasm |
| Molecular Weight | ~61.5 kDa |
| Amino Acids | 543 aa |
| Exons | 4 |
| Pathways | Amyloid, ubiquitin-proteasome |
| UniProt ID | P07196 |
| NCBI Gene ID | 4747 |
| Ensembl ID | ENSG00000104825 |
| OMIM | 162280 |
| GeneCards | NEFL |
| Human Protein Atlas | NEFL |
| Associated Diseases | ALS, Aging, Alzheimer, Amyotrophic Lateral Sclerosis, Dementia |
| Interactions | GFAP, TMEM119, UCHL1, UBIQUITIN, APOE, APOE4 |
| KG Connections | 282 knowledge graph edges |
| Databases | GeneCardsHPASTRING |