| Gene Symbol | PPARAPROTEIN |
| Chromosome | 22 |
| Protein Type | Transcription Factor |
| Function | is a protein involved in cellular signaling and transcriptional regulation. |
| Molecular Weight | 52 kDa |
| GeneCards | PPARAPROTEIN |
| Human Protein Atlas | PPARAPROTEIN |
| PPARGC1A (PGC-1α) | Master coactivator coupling PPARA signaling to mitochondrial biogenesis |
| TFEB | Autophagy regulator downstream of PPARA |
| RXR (Retinoid X Receptor) | Essential PPARA heterodimerization partner |
| Fibrates | PPARA-activating pharmaceuticals under investigation |
| NF-κB | Inflammatory pathway suppressed by PPARA |
| Amyloid-beta and Alpha-synuclein | Pathogenic proteins cleared through |
| Associated Diseases | AD, ADH, AMI, AUTOPHAGY, Als, Alzheimer disease |
| Known Drugs/Compounds | gemfibrozil, Wy14643, Bezafibrate, rapamycin |
| Interactions | ULK1, STX17, SQSTM1, NOS3, STING1, GLP1R |
| SciDEX Hypotheses | Cell-Type Specific Metabolic Reprogramming |
| KG Connections | 542 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |