| Gene Symbol | SLC2A1 |
| Full Name | Glucose Transporter Type 1 (Solute Carrier Family 2 Member 1) |
| Chromosome | 1p34.2 |
| Protein Type | Transporter |
| Function | is a facilitative glucose transporter belonging to the SLC2A family that provides the critical link between systemic glucose supply and cerebral energy metabolism. |
| Primary Expression | BBB endothelium, erythrocytes, astrocytic endfeet, oligodendrocytes |
| Subcellular Localization | Plasma membrane (apical and basolateral in endothelial cells) |
| Molecular Weight | 54 kDa (glycosylated) |
| Amino Acids | 492 aa |
| Exons | 10 |
| Pathways | Ferroptosis, Mapk, Oxidative Stress, autophagy pathway, unfolded protein response |
| UniProt ID | P11166 |
| NCBI Gene ID | 6513 |
| Ensembl ID | ENSG00000117394 |
| OMIM | 138140 |
| GeneCards | SLC2A1 |
| Human Protein Atlas | SLC2A1 |
| Associated Diseases | Als, Ataxia, Cancer, Carcinoma, Infection, Ms |
| Interactions | COX4I1, GSK3B, IGF1, PPAR, MEF2C, NRF2 |
| KG Connections | 234 knowledge graph edges |
| Databases | GeneCardsHPASTRING |