| Gene Symbol | SORTILIN |
| Aliases | SORTILINPROTEIN |
| Function | Sortilin is a member of the vacuolar protein sorting 10 (VPS10) domain receptor family that functions as a multifunctional sorting receptor involved in intracellular trafficking, protein degradatio... |
| Molecular Weight | 100 kDa |
| Amino Acids | 600 aa |
| Pathways | Neurotrophic Signaling, Synaptic Plasticity |
| GeneCards | SORTILIN |
| Human Protein Atlas | SORTILIN |
| Transmembrane domain | A single-pass transmembrane helix anchors sortilin in cellular membranes. |
| Cytoplasmic tail | Contains trafficking motifs (NPXY, dileucine) that direct endocytosis and intracellular sorting. |
| Associated Diseases | Alzheimer'S Disease, disease |
| Interactions | BDNF, IGF2R, TRANSFERRIN |
| KG Connections | 34 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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