protein

RAG1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAG1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

12Outgoing

2Incoming

0Experiments

Summary

Page for RAG1 Protein

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🔬 Protein Info

Gene Symbol	RAG1
Function	The RAG1 protein is a large 270 kDa protein that forms a complex with RAG2 to mediate V(D)J recombination.
Molecular Weight	270 kDa
GeneCards	RAG1
Human Protein Atlas	RAG1
Associated Diseases	Infection
Interactions	EGR2, IFNG, CD38, IL-10
KG Connections	14 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (6)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    RAG1["RAG1"]
    RAG1 -->|"activates"| EGR2["EGR2"]
    RAG1 -->|"activates"| Macrophage["Macrophage"]
    RAG1 -->|"activates"| MONOCYTE["MONOCYTE"]
    RAG1 -->|"activates"| ENDOTHELIAL["ENDOTHELIAL"]
    RAG1 -->|"activates"| HYPOTHALAMUS["HYPOTHALAMUS"]
    RAG1 -->|"activates"| IFNG["IFNG"]
    RAG1 -->|"activates"| Infection["Infection"]
    CD38["CD38"] -->|"activates"| RAG1
    IL_10["IL-10"] -->|"activates"| RAG1

Outgoing (12)

Target	Relation	Type	Str
EGR2	activates	gene	0.50
Macrophage	activates	cell_type	0.50
MONOCYTE	activates	concept	0.50
Infection	associated_with	disease	0.50
ENDOTHELIAL	activates	concept	0.50
HYPOTHALAMUS	activates	concept	0.50
IFNG	activates	gene	0.50
Infection	activates	disease	0.50
T Cell	associated_with	cell_type	0.50
T CELLS	associated_with	concept	0.50
Infection	protects_against	disease	0.50
IFNG	associated_with	gene	0.50

Incoming (2)

Source	Relation	Type	Str
CD38	activates	gene	0.50
IL-10	activates	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

RAG1

Understanding Entity Pages

Summary

Wiki Pages (6)

NPRL2 Gene

LIG4

XRCC4

RAG2 Protein

RAG1 Protein