EGR2

Understanding Entity Pages

This page aggregates everything SciDEX knows about EGR2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

EGR2 is a gene implicated in neurodegeneration research. Key relationships include: biomarker for, inhibits, regulates. Associated with ALS, Als, Cancer. Connected to 59 entities in the SciDEX knowledge graph.

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graph TD
    EGR2["<b>EGR2</b>"]
    RAB37["RAB37"]
    EGR2 -->|"activates"| RAB37
    Cancer{"Cancer"}
    EGR2 -->|"inhibits"| Cancer
    Als{"Als"}
    EGR2 -->|"activates"| Als
    Tumor{"Tumor"}
    EGR2 -->|"inhibits"| Tumor
    Inflammation{"Inflammation"}
    EGR2 -->|"inhibits"| Inflammation
    EGR2 -->|"biomarker for"| Als
    EGR2 -->|"associated with"| Cancer
    EGR2 -->|"associated with"| Inflammation
    EGR2 -->|"associated with"| Tumor
    EGR2 -->|"regulates"| Als
    Ms{"Ms"}
    EGR2 -->|"regulates"| Ms
    ALS{"ALS"}
    EGR2 -->|"activates"| ALS
    NAMPT["NAMPT"]
    NAMPT -->|"inhibits"| EGR2
    SIRT6["SIRT6"]
    SIRT6 -->|"inhibits"| EGR2
    TRAF6["TRAF6"]
    TRAF6 -->|"biomarker for"| EGR2
    P38["P38"]
    P38 -->|"biomarker for"| EGR2
    CD4["CD4"]
    CD4 -->|"biomarker for"| EGR2
    CD38["CD38"]
    CD38 -->|"activates"| EGR2
    SOX2["SOX2"]
    SOX2 -->|"regulates"| EGR2
    MTOR["MTOR"]
    MTOR -->|"regulates"| EGR2
    TAZ["TAZ"]
    TAZ -->|"regulates"| EGR2
    JUN["JUN"]
    JUN -->|"regulates"| EGR2
    FLNA["FLNA"]
    FLNA -->|"biomarker for"| EGR2
    NFKBIA["NFKBIA"]
    NFKBIA -->|"biomarker for"| EGR2
    style EGR2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0