Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ST3GAL3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ST3GAL3 |
| Key Genes/Proteins | ST3GAL2, MYELIN, EPILEPSY, GAL, Ras, Rb |
| Related Diseases | Als, Epilepsy, ALS |
| Related Pathways | Sphingolipid, Myelination |
graph TD
ST3GAL3["ST3GAL3"]
ST3GAL3 -->|"regulates"| GT1b_Biosynthesis["GT1b Biosynthesis"]
ST3GAL3 -->|"inhibits"| Als["Als"]
ST3GAL3 -->|"inhibits"| Epilepsy["Epilepsy"]
ST3GAL3 -->|"inhibits"| ALS["ALS"]
ST3GAL3 -->|"inhibits"| Neuron["Neuron"]
ST3GAL3 -->|"expressed in"| Sphingolipid["Sphingolipid"]
ST3GAL3 -->|"inhibits"| MYELIN["MYELIN"]
ST3GAL3 -->|"inhibits"| Myelination["Myelination"]
ST3GAL2["ST3GAL2"] -->|"co_expressed_with"| ST3GAL3
GAL["GAL"] -->|"expressed in"| ST3GAL3
MYELIN -->|"inhibits"| ST3GAL3
EPILEPSY["EPILEPSY"] -->|"inhibits"| ST3GAL3
GENES["GENES"] -->|"expressed in"| ST3GAL3
AND["AND"] -->|"expressed in"| ST3GAL3| Target | Relation | Type | Str |
|---|---|---|---|
| GT1b Biosynthesis | regulates | process | 0.95 |
| Als | inhibits | disease | 0.65 |
| Epilepsy | inhibits | disease | 0.65 |
| ALS | inhibits | disease | 0.65 |
| Neuron | inhibits | cell_type | 0.60 |
| Sphingolipid | expressed_in | pathway | 0.60 |
| MYELIN | inhibits | gene | 0.60 |
| Myelination | inhibits | pathway | 0.60 |
| ST3GAL2 | expressed_in | gene | 0.60 |
| EPILEPSY | inhibits | gene | 0.60 |
| GAL | expressed_in | gene | 0.60 |
| Ras | expressed_in | protein | 0.60 |
| Rb | inhibits | protein | 0.60 |
| Ras | associated_with | protein | 0.60 |
| Neuron | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||