gene 795 words KG: SYN3
Contents

SYN3 — Synapsin III

🧬 Gene Info
Gene SymbolSYN3
Full NameSynapsin III
Chromosome22q12.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionCerebral cortex, Hippocampus, Synaptic terminals, Retina
Molecular Weight63 kDa
Amino Acids580 aa
UniProt IDO75907
NCBI Gene ID8864
Ensembl IDENSG00000185608
OMIM600731
GeneCardsSYN3
Human Protein AtlasSYN3
N-terminal domain APhosphorylation site for PKA and CaMKII
Central domain CATP-binding site, involved in synaptic vesicle clustering
Associated Diseasesneurodegeneration
Known Drugs/CompoundsPDZ3, PSD95
InteractionsApp, Bdnf, BDNF, DEPRESSION, PSD-95, TRKB
KG Connections18 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

SYN3 interacts_with PSD95
SYN3 interacts_with PDZ3
BDNF activates SYN3
TRKB activates SYN3
SYN3 activates BDNF
SYN3 activates TRKB
SYN3 interacts_with PSD-95
SYN3 activates Depression
SYN3 interacts_with Als
SYN3 activates DEPRESSION

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