PSD95

Understanding Entity Pages

This page aggregates everything SciDEX knows about PSD95: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PSD95 is a gene implicated in neurodegeneration research. Key relationships include: activates, protects against, treats. Associated with Aging, Als, Alzheimer. Connected to 149 entities in the SciDEX knowledge graph.

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graph TD
    PSD95["<b>PSD95</b>"]
    BDNF["BDNF"]
    PSD95 -->|"regulates"| BDNF
    Alzheimer{"Alzheimer"}
    PSD95 -->|"expressed in"| Alzheimer
    Dementia{"Dementia"}
    PSD95 -->|"expressed in"| Dementia
    Als{"Als"}
    PSD95 -->|"expressed in"| Als
    Anxiety{"Anxiety"}
    PSD95 -->|"activates"| Anxiety
    Inflammation{"Inflammation"}
    PSD95 -->|"activates"| Inflammation
    Depression{"Depression"}
    PSD95 -->|"activates"| Depression
    PSD95 -->|"activates"| Alzheimer
    Aging{"Aging"}
    PSD95 -->|"activates"| Aging
    PSD95 -->|"activates"| Als
    Ms{"Ms"}
    PSD95 -->|"activates"| Ms
    PSD95 -->|"expressed in"| Ms
    NLGN1["NLGN1"]
    NLGN1 -->|"interacts with"| PSD95
    CN2097["CN2097"]
    CN2097 -->|"interacts with"| PSD95
    SYN3["SYN3"]
    SYN3 -->|"interacts with"| PSD95
    MMP9["MMP9"]
    MMP9 -->|"expressed in"| PSD95
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"expressed in"| PSD95
    RELA["RELA"]
    RELA -->|"associated with"| PSD95
    OPA1["OPA1"]
    OPA1 -->|"expressed in"| PSD95
    P62["P62"]
    P62 -->|"associated with"| PSD95
    MFN2["MFN2"]
    MFN2 -->|"expressed in"| PSD95
    MBP["MBP"]
    MBP -->|"expressed in"| PSD95
    SYN1["SYN1"]
    SYN1 -->|"activates"| PSD95
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"activates"| PSD95
    style PSD95 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0