Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 113 pages

HistamineKG

entity · 4,009 words · 5 hyp3 ana

MitochondriaKG

entity · 3,769 words · 222 hyp67 ana106 exp

BlarcamesineKG

entity · 3,732 words · 10 hyp41 ana1 exp

PRX005KG

entity · 3,656 words · 9 hyp31 ana5 exp

Amyloid Precursor Protein (APP)KG

entity · 3,485 words · 187 hyp60 ana23 exp

PBKR03KG

entity · 3,476 words · 3 hyp22 ana5 exp

CNTFR GeneKG

entity · 3,392 words · 13 hyp5 ana4 exp

DNL310KG

entity · 3,254 words · 1 hyp1 ana

Litronesib (LY317615/Enzastaurin)KG

entity · 3,236 words · 1 hyp1 ana5 exp

RemternetugKG

entity · 3,163 words · 11 hyp1 ana4 exp

NeuronsKG

entity · 3,010 words · 196 hyp58 ana12 exp

Complement SystemKG

entity · 2,994 words · 29 hyp11 ana12 exp

PR001KG

entity · 2,990 words · 1 hyp19 ana1 exp

PRX012KG

entity · 2,912 words · 10 hyp2 ana

FerroptosisKG

entity · 2,823 words · 59 hyp36 ana15 exp

Entities OverviewKG

entity · 2,746 words · 26 hyp9 ana13 exp

PLD4 (Phospholipase D Family Member 4)KG

entity · 2,727 words · 17 hyp28 ana3 exp

SemorinemabKG

entity · 2,720 words · 7 hyp2 ana3 exp

FosramatineKG

entity · 2,706 words · 13 hyp41 ana2 exp

MTHFR (Methylenetetrahydrofolate Reductase)KG

entity · 2,515 words · 8 hyp4 ana6 exp

AduhelmKG

entity · 2,483 words · 10 hyp2 ana6 exp

AL001 (Latozinemab)KG

entity · 2,467 words · 27 ana2 exp

GT-02287KG

entity · 2,415 words · 1 hyp23 ana1 exp

Mitochondrial DynamicsKG

entity · 2,310 words · 37 hyp22 ana23 exp

CrenezumabKG

entity · 2,284 words · 26 ana6 exp

Autonomic Nervous SystemKG

entity · 2,198 words · 3 hyp3 ana1 exp

GRM1 GeneKG

entity · 2,182 words · 3 hyp2 ana

GRM5 GeneKG

entity · 2,108 words · 3 hyp2 ana

DonepezilKG

entity · 2,068 words · 10 hyp4 ana8 exp

Gamma-Aminobutyric Acid (GABA)KG

entity · 2,056 words · 2 hyp3 ana13 exp

Presenilin-1 (PS1)KG

entity · 1,985 words · 29 hyp16 ana9 exp

ExcitotoxicityKG

entity · 1,922 words · 44 hyp34 ana1 exp

SNX5 (Sorting Nexin 5)KG

entity · 1,920 words · 7 hyp1 ana1 exp

Donanemab (Kisunla)KG

entity · 1,882 words · 18 hyp6 ana7 exp

Glymphatic SystemKG

entity · 1,863 words · 15 hyp15 ana7 exp

DNL151KG

entity · 1,863 words · 20 ana1 exp

Norepinephrine (Noradrenaline)KG

entity · 1,820 words · 3 hyp4 ana6 exp

Serotonin (5-Hydroxytryptamine, 5-HT)KG

entity · 1,815 words · 15 hyp15 ana2 exp

RNF128 (Graf1/XTP3) GeneKG

entity · 1,768 words · 7 hyp3 ana2 exp

BIIB122KG

entity · 1,767 words · 4 hyp17 ana1 exp

SQSTM1/p62KG

entity · 1,760 words · 17 hyp18 ana16 exp

Entities Quality RankingsKG

entity · 1,684 words · 1 hyp1 ana5 exp

Histone ModificationsKG

entity · 1,662 words · 13 hyp2 ana5 exp

CalpainsKG

entity · 1,651 words · 5 hyp1 ana1 exp

ExosomesKG

entity · 1,639 words · 59 hyp42 ana1 exp

Expand Microtubules contentKG

entity · 1,565 words · 5 hyp1 ana

Expand Hsp90 contentKG

entity · 1,548 words · 10 hyp9 ana1 exp

PSD-95 (Postsynaptic Density Protein 95)KG

entity · 1,511 words · 54 hyp46 ana6 exp

DopamineKG

entity · 1,485 words · 130 hyp53 ana64 exp

Tumor Necrosis Factor (TNF)KG

entity · 1,483 words · 131 hyp53 ana20 exp

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