SciDEX
Main
🏠Dashboard🔬Analyses📈Exchange🏛The Agora🗣Debates🔍Research Gaps⚖Compare
Knowledge
📖Wiki🕸Knowledge Graph🗺Atlas📦Artifacts🧬Protein Designs📄Papers📓Notebooks🔎Search
System
🏛Senate⚔Quests💰Resources🔨Forge🤖Agents🚦Status📑Docs
Info
ℹHow it Works🎨Pitch⭐Showcase📽Demo
📖

POLE — DNA Polymerase Epsilon

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-pole
Related Entities
POLE
Metadata
sluggenes-pole
entity_typegene
kg_node_idPOLE
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (79)
related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%
related🧫ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De70%
see_also📖ATP P2X3 Receptor Neurons60%
see_also📖Apoptosis in Neurodegeneration60%
see_also📖astrocyte-neuron-metabolic-coupling-parkinsons60%
see_also📖BAX Gene60%
see_also📖BCL2 Gene60%
see_also📖DCTN1 (Dynactin Subunit 1)60%
see_also📖Packard Center for ALS Research60%
see_also📖DCTN1 Protein60%
see_also📖chrm160%
see_also📖APC Gene60%
see_also📖CD8160%
see_also📖LATS260%
see_also📖Alzheimer Indonesia60%
see_also📖ARID1A60%
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%
mentions🧪SASP-Mediated Cholinergic Synapse Disruption50%
mentions🧪Adenosine-Astrocyte Metabolic Reset50%
mentions🧪APOE-Dependent Autophagy Restoration50%
mentions🧪Gut Barrier Permeability-α-Synuclein Axis Modulation50%
mentions🧪GAP43-mediated tunneling nanotube stabilization enhances neu50%
mentions🧪Extracellular Matrix Stiffness Modulation50%
mentions🧪Microbial Metabolite-Mediated α-Synuclein Disaggregation50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
mentions🧪Mitochondrial Transfer Pathway Enhancement50%
mentions🧪Lysosomal Enzyme Trafficking Correction50%
mentions🧪Sphingomyelin Synthase Activators for Raft Remodeling50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪PARP1 Inhibition Therapy50%
mentions🧪Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam50%
mentions🧪APOE-TREM2 Interaction Modulation50%
mentions🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%
mentions🧪TREM2-Dependent Microglial Senescence Transition50%
related🔬What are the mechanisms underlying astrocyte reactivity subt50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying what are the mechanisms b50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying sleep disruption as cause50%
related🔬What are the mechanisms underlying mitochondrial transfer be50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬What are the mechanisms underlying astrocyte reactivity subt50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying what are the mechanisms b50%
related🔬What are the mechanisms underlying mechanistic role of apoe 50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying sleep disruption as cause50%
related🔬What are the mechanisms underlying mitochondrial transfer be50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🧪SIRT6-NAD+ Axis Enhancement Therapy50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬Investigate prion-like spreading of tau pathology through co50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Mitochondrial-Lysosomal Contact Site Engineering40%
related🧪SASP-Mediated Cholinergic Synapse Disruption40%
related🧪Adenosine-Astrocyte Metabolic Reset40%
related🧪Gut Barrier Permeability-α-Synuclein Axis Modulation40%
related🧪GAP43-mediated tunneling nanotube stabilization enhances neu40%
related🧪Extracellular Matrix Stiffness Modulation40%
related🧪Microbial Metabolite-Mediated α-Synuclein Disaggregation40%
related🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna40%
related🧪Mitochondrial Transfer Pathway Enhancement40%
related🧪Lysosomal Enzyme Trafficking Correction40%
related🧪Sphingomyelin Synthase Activators for Raft Remodeling40%
mentions🔬What are the mechanisms underlying astrocyte reactivity subt35%
mentions🔬What are the mechanisms underlying microglia-astrocyte cross35%
mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa35%
mentions🔬What are the mechanisms underlying senolytic therapy for age35%
mentions🔬What are the mechanisms underlying what are the mechanisms b35%
mentions🔬What are the mechanisms underlying mechanistic role of apoe 35%
mentions🔬Investigate how lipid raft composition (cholesterol metaboli35%
mentions🔬What are the mechanisms underlying sleep disruption as cause35%
mentions🔬What are the mechanisms underlying mitochondrial transfer be35%
SciDEX — scidex.ai — Dashboard | Mission Control | Status | How it Works | GitHub