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Beclin-1

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-proteins-beclin-1
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BECLIN1
Metadata
slugproteins-beclin-1
entity_typeprotein
kg_node_idBECLIN1
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Linked Artifacts (58)
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering65%
mentions🧪APOE-Dependent Autophagy Restoration65%
mentions🧪Autophagosome Maturation Checkpoint Control65%
mentions🧪Transcriptional Autophagy-Lysosome Coupling65%
mentions🧫CLOCK/BMAL1 regulation of ICC autophagy in GERD model60%
mentions🧫Autophagy Enhancement Drug Screening for Neurodegeneration60%
mentions🧫Macroautophagy Dysfunction in PD - Experiment Design60%
see_also📖AMPK (AMP-Activated Protein Kinase)60%
see_also📖Apoptosis in Neurodegeneration60%
see_also📖ACTB Gene60%
see_also📖AKT1 Gene60%
see_also📖Alzheimer Indonesia60%
see_also📖Amyloid-Related Imaging Abnormalities (ARIA)60%
see_also📖ambra160%
see_also📖APAF1 Gene60%
related🧪Mitochondrial-Lysosomal Contact Site Engineering58%
related🧪APOE-Dependent Autophagy Restoration58%
related🧪Autophagosome Maturation Checkpoint Control58%
related🧪Transcriptional Autophagy-Lysosome Coupling58%
related🧫CLOCK/BMAL1 regulation of ICC autophagy in GERD model54%
related🧫Autophagy Enhancement Drug Screening for Neurodegeneration54%
related🧫Macroautophagy Dysfunction in PD - Experiment Design54%
mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%
mentions🧪Chaperone-Mediated APOE4 Refolding Enhancement50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Lysosomal Positioning Dynamics Modulation50%
mentions🧪Partial Neuronal Reprogramming via Modified Yamanaka Cocktai50%
mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%
mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration50%
mentions🧪SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK50%
mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering50%
mentions🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction50%
mentions🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling50%
mentions🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying mitochondrial transfer be50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying mitochondrial transfer be50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🧪APOE-Dependent Autophagy Restoration50%
related🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors50%
related🔬Epigenetic reprogramming in aging neurons50%
mentions📖Z-index Pharma40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪HSP90-Tau Disaggregation Complex Enhancement40%
related🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m40%
related🧪Chaperone-Mediated APOE4 Refolding Enhancement40%
mentions🔬What are the mechanisms underlying apoe4 structural biology 35%
mentions🔬Investigate prion-like spreading of tau pathology through co35%