ERCC3

Understanding Entity Pages

This page aggregates everything SciDEX knows about ERCC3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ERCC3 is a gene implicated in neurodegeneration research. Key relationships include: activates, associated with, risk factor for. Associated with ALS, Als, Carcinoma. Connected to 35 entities in the SciDEX knowledge graph.

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graph TD
    ERCC3["<b>ERCC3</b>"]
    Cirrhosis{"Cirrhosis"}
    ERCC3 -->|"activates"| Cirrhosis
    Carcinoma{"Carcinoma"}
    ERCC3 -->|"activates"| Carcinoma
    Ms{"Ms"}
    ERCC3 -->|"activates"| Ms
    Als{"Als"}
    ERCC3 -->|"activates"| Als
    ERCC3 -->|"associated with"| Als
    ERCC3 -->|"associated with"| Carcinoma
    ERCC3 -->|"associated with"| Cirrhosis
    ALS{"ALS"}
    ERCC3 -->|"activates"| ALS
    CEBPB["CEBPB"]
    ERCC3 -->|"activates"| CEBPB
    Pi3K(["Pi3K"])
    ERCC3 -->|"activates"| Pi3K
    Mtor(["Mtor"])
    ERCC3 -->|"activates"| Mtor
    Akt(["Akt"])
    ERCC3 -->|"activates"| Akt
    EGF["EGF"]
    EGF -->|"activates"| ERCC3
    CYP3A4["CYP3A4"]
    CYP3A4 -->|"activates"| ERCC3
    PDK1["PDK1"]
    PDK1 -->|"activates"| ERCC3
    MTOR["MTOR"]
    MTOR -->|"activates"| ERCC3
    EGFR["EGFR"]
    EGFR -->|"activates"| ERCC3
    CYP1A2["CYP1A2"]
    CYP1A2 -->|"activates"| ERCC3
    AKT["AKT"]
    AKT -->|"activates"| ERCC3
    CEBPB -->|"activates"| ERCC3
    PI3K["PI3K"]
    PI3K -->|"activates"| ERCC3
    CCL2["CCL2"]
    CCL2 -->|"activates"| ERCC3
    style ERCC3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0