Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FEATURE DEGS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FEATURE DEGS |
| Key Genes/Proteins | IMMUNE INFILTRATION, NF-ΚB, TNF, NAMPT, TNF-Α, HUB GENES |
| Related Diseases | COPD, Inflammation |
| Related Pathways | Nf-Κb |
graph TD
FEATURE_DEGS["FEATURE DEGS"]
FEATURE_DEGS -->|"causes"| COPD["COPD"]
FEATURE_DEGS -->|"causes"| AND["AND"]
FEATURE_DEGS ---|"associated"| Inflammation["Inflammation"]
FEATURE_DEGS ---|"associated"| IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
FEATURE_DEGS ---|"associated"| Nf__b["Nf-Kappab"]
FEATURE_DEGS ---|"associated"| NF__B["NF-KappaB"]
FEATURE_DEGS ---|"associated"| TNF["TNF"]
AND -->|"causes"| FEATURE_DEGS
GENES["GENES"] ---|"associated"| FEATURE_DEGS
INFLAMMATION["INFLAMMATION"] ---|"associated"| FEATURE_DEGS
TNF ---|"associated"| FEATURE_DEGS
NF__B ---|"associated"| FEATURE_DEGS
RNA["RNA"] ---|"associated"| FEATURE_DEGS| Target | Relation | Type | Str |
|---|---|---|---|
| COPD | causes | disease | 0.80 |
| Inflammation | associated_with | disease | 0.65 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
| Nf-Κb | associated_with | pathway | 0.60 |
| NF-ΚB | associated_with | gene | 0.60 |
| TNF | associated_with | gene | 0.60 |
| NAMPT | associated_with | gene | 0.60 |
| TNF-Α | associated_with | gene | 0.60 |
| HUB GENES | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| AND | causes | gene | 0.60 |
| PTGS2 | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GENES | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| TNF | associated_with | gene | 0.60 |
| NF-ΚB | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| AND | causes | gene | 0.60 |
| NAMPT | associated_with | gene | 0.60 |
| HUB GENES | associated_with | gene | 0.60 |
| PTGS2 | associated_with | gene | 0.60 |
| TNF-Α | associated_with | gene | 0.60 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||