Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GUT DYSBIOSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GUT DYSBIOSIS |
graph TD
GUT_DYSBIOSIS["GUT DYSBIOSIS"]
GUT_DYSBIOSIS -->|"causes"| Gut_Brain_Axis_Dysfunction["Gut-Brain Axis Dysfunction"]
GUT_DYSBIOSIS -->|"causes"| Blood_Brain_Barrier_Permeabili["Blood-Brain Barrier Permeability"]
GUT_DYSBIOSIS -->|"causes"| Neuroinflammation["Neuroinflammation"]
GUT_DYSBIOSIS -->|"causes"| Gut_Brain_Axis["Gut-Brain Axis"]
GUT_DYSBIOSIS -->|"promotes"| neuroinflammation["neuroinflammation"]
GUT_DYSBIOSIS -->|"causes"| Parkinson_s_disease["Parkinson's disease"]
Probiotic_Supplementation["Probiotic Supplementation"] -->|"treats"| GUT_DYSBIOSIS
Rotenone["Rotenone"] -->|"causes"| GUT_DYSBIOSIS| Target | Relation | Type | Str |
|---|---|---|---|
| SCFA deficiency | causes | Metabolic state | 1.00 |
| Gut-Brain Axis Dysfunction | causes | process | 0.92 |
| Neuroinflammation | causes | process | 0.90 |
| Blood-Brain Barrier Permeability | causes | process | 0.90 |
| Butyrate | associated_with | compound | 0.90 |
| Gut-Brain Axis | causes | pathway | 0.85 |
| Parkinson's Disease | associated_with | disease | 0.85 |
| Alzheimer's Disease | contributes_to | disease | 0.85 |
| Neurodegeneration | associated_with | process | 0.85 |
| Neuroinflammation | contributes_to | process | 0.80 |
| Butyrate | downregulates | compound | 0.80 |
| Parkinson's Disease | contributes_to | disease | 0.75 |
| neuroinflammation | promotes | process | 0.75 |
| cirrhosis | associated_with | disease | 0.70 |
| glaucoma | associated_with | disease | 0.70 |
| Amyloid-beta Aggregation | associated_with | biological_process | 0.70 |
| Th17 homeostatic cells | inhibits | cell_type | 0.70 |
| Parkinson Disease | associated_with | disease | 0.70 |
| Parkinson's disease | causes | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Lactococcus Lactis Mg1363-Pmg36E-Glp-1 | associated_with | drug | 0.90 |
| Mitochondrial Dysfunction | causes | disease | 0.85 |
| Probiotic Supplementation | treats | drug | 0.80 |
| Rotenone | causes | compound | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 4 hypotheses Top: 7.200
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.00 · 2026-04-26
closed · Rounds: 4 · Score: 0.00 · 2026-04-26
closed · Rounds: 4 · Score: 0.00 · 2026-04-26
closed · Rounds: 4 · Score: 0.00 · 2026-04-26
active · Rounds: 4 · Score: 1.00 · 2026-04-26
Hypotheses and analyses mentioning GUT DYSBIOSIS in their description or question text
No additional research found