concept

IMMUNE SYSTEM

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IMMUNE SYSTEM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

40Connections
0Hypotheses
1Analyses
23Outgoing
17Incoming
0Experiments

No summary available yet. View on Wiki →

💡 Concept Info
NameIMMUNE SYSTEM

Wiki Pages (20)

Knowledge base pages for this entity

Parkinson's Disease

disease · 8807 words

Alpha-Synuclein Pathology

mechanism · 6288 words

PD Combination Therapy Matrix

mechanism · 5949 words

nhp-validation-animal-model

general · 5820 words

neuroinflammation

mechanism · 5462 words

Pathway Diagram

graph TD
    IMMUNE_SYSTEM["IMMUNE SYSTEM"]
    IMMUNE_SYSTEM -->|"interacts"| Nervous_System["Nervous System"]
    IMMUNE_SYSTEM -->|"involved_in"| Neuropathic_Pain["Neuropathic Pain"]
    IMMUNE_SYSTEM -->|"contributes to"| Biological_Aging["Biological Aging"]
    IMMUNE_SYSTEM -->|"involved_in"| Pathogen_Elimination["Pathogen Elimination"]
    IMMUNE_SYSTEM -->|"contributes to"| Autoimmune_Diseases["Autoimmune Diseases"]
    IMMUNE_SYSTEM -->|"mediates"| Microbiota_Gut_Brain_Axis["Microbiota-Gut-Brain Axis"]
    IMMUNE_SYSTEM -.protects against.-> Infectious_Diseases["Infectious Diseases"]
    IMMUNE_SYSTEM -->|"regulates"| mood_regulation["mood regulation"]
    Microbiota["Microbiota"] -->|"interacts"| IMMUNE_SYSTEM
    Gut_Microbiota["Gut Microbiota"] -->|"modulates"| IMMUNE_SYSTEM
    Tumor_Cells["Tumor Cells"] -->|"interacts"| IMMUNE_SYSTEM
    Extracellular_Vesicles["Extracellular Vesicles"] -->|"participates in"| IMMUNE_SYSTEM
    IFN_gamma["IFN-gamma"] -->|"regulates"| IMMUNE_SYSTEM
    Testosterone["Testosterone"] -->|"regulates"| IMMUNE_SYSTEM

Outgoing (23)

TargetRelationTypeStr
Nervous Systeminteracts_withprocess0.95
Neuropathic Paininvolved_indisease0.95
Biological Agingcontributes_toprocess0.95
Pathogen Eliminationinvolved_inprocess0.95
Autoimmune Diseasescontributes_todisease0.95

Incoming (17)

SourceRelationTypeStr
APOEinvolved_ingene0.92
Glycosylation Changesassociated_withprocess0.90
Epitheliuminteracts_withcell_type0.90
Microbiotainteracts_withprocess0.90
Gut Microbiotamodulatesprocess0.88

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Systemic immune profiling and peripheral immune contributions to neurodegenerati

neurodegeneration | 2026-04-04 | 0 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found