Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KYNURENINE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| HUNTINGTIN | interacts_with | protein | 0.65 |
| CXCL10 | inhibits | gene | 0.65 |
| CXCL10 | activates | gene | 0.65 |
| NEURODEGENERATION | interacts_with | disease | 0.65 |
| CYTOKINES | produces | phenotype | 0.65 |
| CYTOKINES | activates | phenotype | 0.65 |
| OXIDATIVE STRESS | activates | phenotype | 0.65 |
| INFLAMMATION | interacts_with | phenotype | 0.65 |
| MICROGLIA | activates | cell_type | 0.65 |
| CYTOKINES | regulates | phenotype | 0.65 |
| NEURODEGENERATION | activates | disease | 0.65 |
| LIPID PEROXIDATION | causes | phenotype | 0.65 |
| NICOTINAMIDE | activates | drug | 0.65 |
| ASTROCYTE | treats | cell_type | 0.65 |
| NEURODEGENERATION | expressed_in | disease | 0.55 |
| CYTOKINES | implicated_in | phenotype | 0.55 |
| TNF | associated_with | gene | 0.45 |
| HUNTINGTON'S DISEASE | associated_with | disease | 0.45 |
| MELATONIN | associated_with | drug | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| KYNURENINE PATHWAY | associated_with | pathway | 0.45 |
| NEUROINFLAMMATION | associated_with | phenotype | 0.45 |
| HIPPOCAMPUS | associated_with | brain_region | 0.45 |
| NICOTINAMIDE | associated_with | drug | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||