protein

LCKPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LCKPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Lck — Proto Oncogene Tyrosine Protein Kinase Lck is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	LCKPROTEIN
Protein Family	Src family non-receptor tyrosine kinases
Protein Type	Receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	T-lymphocytes where it is essential for T-cell receptor (TCR) signaling and T-cell development
Subcellular Localization	Plasma membrane, Cytoplasm
Molecular Weight	57 kDa
UniProt ID	P06239
GeneCards	LCKPROTEIN
Human Protein Atlas	LCKPROTEIN
Protein Name	Proto-Oncogene Tyrosine-Protein Kinase Lck
Gene	LCK
Associated Diseases	Aging, Als, Alzheimer
Interactions	FYN, SRC, TCR, CD4, MAPK3, ZAP70
KG Connections	67 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Lck — Proto-Oncogene Tyrosine-Protein Kinase Lck

protein · 536 words

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Pathway Diagram

graph TD
    LCKPROTEIN["LCKPROTEIN"]
    neurodegeneration["neurodegeneration"]
    LCKPROTEIN -->|"implicated_in"| neurodegeneration
    style LCKPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found