Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MC3R: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| autophagy | activates | process | 0.95 |
| hepatocyte | expressed_in | cell_type | 0.95 |
| Lipid Droplet Autophagy | regulates | process | 0.95 |
| Liver Steatosis | regulates | disease | 0.95 |
| Autophagy | regulates | process | 0.95 |
| lipid droplet clearance | regulates | process | 0.90 |
| liver steatosis | suppresses | disease | 0.90 |
| triglyceride accumulation | suppresses | phenotype | 0.90 |
| Map1Lc3 | upregulates | protein | 0.85 |
| TFEB | modulates | protein | 0.85 |
| autophagosome-lysosome docking | promotes | process | 0.85 |
| Metabolic-associated fatty liver disease | therapeutic_target | disease | 0.85 |
| Lipid Metabolism | regulates | process | 0.85 |
| mitochondrial respiration | upregulates | process | 0.80 |
| energy expenditure | promotes | phenotype | 0.80 |
| body weight | suppresses | phenotype | 0.80 |
| lipolysis | regulates | process | 0.80 |
| TFEB | activates | gene | 0.60 |
| TFEB | regulates | gene | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| MTORC1 | regulates | gene | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||