concept

MIR-375

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR-375: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

39Connections

0Hypotheses

0Analyses

20Outgoing

12Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	MIR-375
Key Genes/Proteins	CANCER, JUN, AND, GSS, SLC16A2, CYP2E1
Related Diseases	Acetaminophen-Induced Acute Liver Failure, Acute Liver Failure, acetaminophen-induced acute liver failure, Cancer

Wiki Pages (1)

Knowledge base pages for this entity

YWHAH Protein (14-3-3 Eta)

protein · 1947 words

→

Pathway Diagram

graph TD
    MIR_375["MIR-375"]
    MIR_375 -.protects against.-> Acetaminophen_Induced_Acute_Li["Acetaminophen-Induced Acute Liver Failure"]
    MIR_375 -->|"regulates"| Pharmacogene_Expression["Pharmacogene Expression"]
    MIR_375 -.protects against.-> Acute_Liver_Failure["Acute Liver Failure"]
    MIR_375 -.protects against.-> acetaminophen_induced_acute_li["acetaminophen-induced acute liver failure"]
    MIR_375 -->|"modulates"| Acetaminophen["Acetaminophen"]
    MIR_375 -->|"expressed in"| Liver["Liver"]
    CYP2E1["CYP2E1"] -->|"activates"| MIR_375
    GSS["GSS"] -->|"activates"| MIR_375
    JUN["JUN"] -->|"activates"| MIR_375
    ACSL5["ACSL5"] -->|"activates"| MIR_375
    SLC16A2["SLC16A2"] -->|"activates"| MIR_375
    MICRORNAS["MICRORNAS"] -->|"activates"| MIR_375
    CANCER["CANCER"] -->|"target for"| MIR_375

Outgoing (27)

Target	Relation	Type	Str
Acetaminophen-Induced Acute Liver Failure	protects_against	disease	0.95
Acute Liver Failure	protects_against	disease	0.92
Pharmacogene Expression	regulates	process	0.90
acetaminophen-induced acute liver failure	protects_against	disease	0.90
Acetaminophen	modulates	drug	0.85
Liver	expressed_in	cell_type	0.80
Cancer	activates	disease	0.65
Cancer	therapeutic_target	disease	0.65
CANCER	activates	gene	0.60
JUN	activates	gene	0.60
AND	activates	gene	0.60
GSS	activates	gene	0.60
SLC16A2	activates	gene	0.60
CYP2E1	activates	gene	0.60
MICRORNAS	activates	gene	0.60
JUN	therapeutic_target	gene	0.60
SLC16A2	therapeutic_target	gene	0.60
ACSL5	therapeutic_target	gene	0.60
Actin	therapeutic_target	protein	0.60
App	therapeutic_target	protein	0.60

Incoming (12)

Source	Relation	Type	Str
CYP2E1	activates	gene	0.60
GSS	activates	gene	0.60
JUN	activates	gene	0.60
ACSL5	activates	gene	0.60
SLC16A2	activates	gene	0.60
MICRORNAS	activates	gene	0.60
JUN	therapeutic_target	gene	0.60
CANCER	therapeutic_target	gene	0.60
SLC16A2	therapeutic_target	gene	0.60
ACSL5	therapeutic_target	gene	0.60
AND	activates	gene	0.60
MICRORNAS	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found