concept

MST2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MST2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections
0Hypotheses
0Analyses
5Outgoing
10Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMST2
Key Genes/ProteinsLATS2, HIPPO, AQP4, GATA3, GATA2, NFATC1
Related DiseasesAls, Ms
Related PathwaysHippo Pathway

Wiki Pages (11)

Knowledge base pages for this entity

Hippo Signaling Pathway in Neurodegeneration

mechanism · 1922 words

MST4 Gene

gene · 1709 words

LATS1 — Large Tumor Suppressor Kinase 1, Hippo Pathway

gene · 1653 words

STK4 — Serine/Threonine Kinase 4

gene · 1646 words

Hippo Signaling in 4R-Tauopathies

mechanism · 1518 words

Pathway Diagram

graph TD
    MST2["MST2"]
    MST2 -->|"activates"| LATS2["LATS2"]
    MST2 -->|"regulates"| Cardiovascular["Cardiovascular"]
    MST2 -->|"activates"| Als["Als"]
    MST2 -->|"activates"| Ms["Ms"]
    MST2 -->|"activates"| HIPPO["HIPPO"]
    MST2 -->|"activates"| Hippo_Pathway["Hippo Pathway"]
    AQP4["AQP4"] -->|"expressed in"| MST2
    GATA3["GATA3"] -->|"activates"| MST2
    GATA2["GATA2"] -->|"activates"| MST2
    HIPPO -->|"activates"| MST2
    NFATC1["NFATC1"] -->|"activates"| MST2
    MST1["MST1"] -->|"activates"| MST2
    YAP["YAP"] -->|"activates"| MST2
    AND["AND"] -->|"activates"| MST2

Outgoing (5)

TargetRelationTypeStr
LATS2activatesgene0.80
Alsactivatesdisease0.65
Msactivatesdisease0.65
HIPPOactivatesgene0.60
Hippo Pathwayactivatespathway0.60

Incoming (10)

SourceRelationTypeStr
AQP4expressed_ingene0.60
GATA3activatesgene0.60
GATA2activatesgene0.60
HIPPOactivatesgene0.60
NFATC1activatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found