MST1

Understanding Entity Pages

This page aggregates everything SciDEX knows about MST1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MST1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, therapeutic target. Associated with Als, Alzheimer, Alzheimer's disease. Connected to 72 entities in the SciDEX knowledge graph.

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graph TD
    MST1["<b>MST1</b>"]
    LATS1["LATS1"]
    MST1 -->|"activates"| LATS1
    Cardiovascular["Cardiovascular"]
    MST1 -->|"regulates"| Cardiovascular
    mitochondrial_function(["mitochondrial function"])
    MST1 -->|"regulates"| mitochondrial_function
    oxidative_stress(["oxidative stress"])
    MST1 -->|"activates"| oxidative_stress
    apoptosis(["apoptosis"])
    MST1 -->|"activates"| apoptosis
    Alzheimer_s_disease{"Alzheimer's disease"}
    MST1 -->|"associated with"| Alzheimer_s_disease
    PGC1_["PGC1alpha"]
    MST1 -->|"interacts with"| PGC1_
    mitochondrial_homeostasis(["mitochondrial homeostasis"])
    MST1 -->|"regulates"| mitochondrial_homeostasis
    neuronal_apoptosis(["neuronal apoptosis"])
    MST1 -->|"activates"| neuronal_apoptosis
    MT_ND4L["MT-ND4L"]
    MST1 -->|"regulates"| MT_ND4L
    cognitive_decline(["cognitive decline"])
    MST1 -->|"activates"| cognitive_decline
    cognitive_impairment(["cognitive impairment"])
    MST1 -->|"activates"| cognitive_impairment
    HIPPO["HIPPO"]
    HIPPO -->|"activates"| MST1
    CANCER["CANCER"]
    CANCER -->|"activates"| MST1
    CGAS_STING["CGAS-STING"]
    CGAS_STING -->|"activates"| MST1
    STING["STING"]
    STING -->|"activates"| MST1
    MT_ATP6["MT-ATP6"]
    MT_ATP6 -->|"regulates"| MST1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"regulates"| MST1
    PI3K["PI3K"]
    PI3K -->|"regulates"| MST1
    HIPPO -->|"regulates"| MST1
    AKT["AKT"]
    AKT -->|"regulates"| MST1
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"regulates"| MST1
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MITOCHONDRIAL_DYSFUNCTION -->|"inhibits"| MST1
    MT_CO2["MT-CO2"]
    MT_CO2 -->|"regulates"| MST1
    style MST1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0