LATS2

Understanding Entity Pages

This page aggregates everything SciDEX knows about LATS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

LATS2 is a gene implicated in neurodegeneration research. Key relationships include: activates, therapeutic target, inhibits. Associated with Als, Alzheimer, Cancer. Connected to 30 entities in the SciDEX knowledge graph.

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graph TD
    LATS2["<b>LATS2</b>"]
    Cardiovascular["Cardiovascular"]
    LATS2 -->|"regulates"| Cardiovascular
    Cancer{"Cancer"}
    LATS2 -->|"inhibits"| Cancer
    Ms{"Ms"}
    LATS2 -->|"activates"| Ms
    Tumor{"Tumor"}
    LATS2 -->|"activates"| Tumor
    Als{"Als"}
    LATS2 -->|"activates"| Als
    Alzheimer{"Alzheimer"}
    LATS2 -->|"therapeutic target"| Alzheimer
    RAB27A["RAB27A"]
    LATS2 -->|"activates"| RAB27A
    MICRORNAS["MICRORNAS"]
    LATS2 -->|"inhibits"| MICRORNAS
    YAP["YAP"]
    LATS2 -->|"inhibits"| YAP
    APOPTOSIS["APOPTOSIS"]
    LATS2 -->|"activates"| APOPTOSIS
    LATS2 -->|"activates"| YAP
    Apoptosis(["Apoptosis"])
    LATS2 -->|"activates"| Apoptosis
    MST2["MST2"]
    MST2 -->|"activates"| LATS2
    YAP -->|"inhibits"| LATS2
    RAB27A -->|"activates"| LATS2
    HIPPO["HIPPO"]
    HIPPO -->|"activates"| LATS2
    LATS1["LATS1"]
    LATS1 -->|"activates"| LATS2
    TAZ["TAZ"]
    TAZ -->|"activates"| LATS2
    TCF3["TCF3"]
    TCF3 -->|"therapeutic target"| LATS2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"therapeutic target"| LATS2
    AXIN["AXIN"]
    AXIN -->|"therapeutic target"| LATS2
    CANCER["CANCER"]
    CANCER -->|"inhibits"| LATS2
    AND["AND"]
    AND -->|"activates"| LATS2
    style LATS2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0