Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYT1L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | MYT1L |
| Full Name | Myelin Transcription Factor 1 Like |
| Chromosome | 2p25.3 |
| Protein Type | Transcription Factor |
| Function | is a zinc finger transcription factor that plays a critical role in neuronal development, differentiation, and maintenance. |
| Primary Expression | Brain (neurons), spinal cord |
| Molecular Weight | 120 kDa |
| Gene Type | Protein coding |
| UniProt ID | Q9UL36 |
| NCBI Gene ID | 23040 |
| Ensembl ID | ENSG00000116254 |
| OMIM | 613084 |
| GeneCards | MYT1L |
| Human Protein Atlas | MYT1L |
| Associated Diseases | Als, Alzheimer |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["MYT1L"]
N1["Alzheimer"]
N0 -->|"associated with"| N1
N2["Als"]
N0 -->|"associated with"| N2
N3["APP"]
N0 -->|"associated with"| N3
N4["VGF"]
N0 -->|"associated with"| N4
N5["Microglia"]
N0 -->|"associated with"| N5
N6["APOE"]
N6 -->|"associated with"| N0
N7["PIN1"]
N7 -->|"causes"| N0
N8["RPL24"]
N8 -->|"associated with"| N0
N9["ALZHEIMER"]
N9 -->|"associated with"| N0
N10["HSPB1"]
N10 -->|"associated with"| N0
N11["MITOCHONDRIA"]
N11 -->|"associated with"| N0
N12["CD44"]
N12 -->|"associated with"| N0
N13["MICROGLIA"]
N13 -->|"associated with"| N0
N14["MICRORNAS"]
N14 -->|"causes"| N0
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classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
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classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 disease
class N2 disease
class N3 gene
class N4 gene
class N6 gene
class N7 gene
class N8 gene
class N9 gene
class N10 gene
class N11 gene
class N12 gene
class N13 gene
class N14 gene| Source | Relation | Type | Str |
|---|---|---|---|
| ALZHEIMER | associated_with | gene | 0.60 |
| HSPB1 | associated_with | gene | 0.60 |
| MITOCHONDRIA | associated_with | gene | 0.60 |
| MICROGLIA | associated_with | gene | 0.60 |
| MICRORNAS | causes | gene | 0.60 |
| AMYLOID | associated_with | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| PIN1 | causes | gene | 0.60 |
| RPL24 | associated_with | gene | 0.60 |
| CD44 | associated_with | gene | 0.60 |
| RPS23 | associated_with | gene | 0.60 |
| GFAP | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity