protein

P53PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about P53PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

Summary

Tumor Protein P53 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	P53PROTEIN
Protein Type	Transcription Factor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	signals The protein functions as a homotetramer, with each monomer containing 3
Amino Acids	4477 aa
GeneCards	P53PROTEIN
Human Protein Atlas	P53PROTEIN
Associated Diseases	ALS, Aging, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/Compounds	RAPAMYCIN, chemotherapy, Thiabendazole, selinexor, rapamycin, MDM2 antagonist Nutlin-3
Interactions	AMPK, BECN1, RPTOR, HTRA2, ULK1, PRKAA2
KG Connections	2628 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Tumor Protein P53

protein · 599 words

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Pathway Diagram

graph TD
    P53PROTEIN["P53PROTEIN"]
    neurodegeneration["neurodegeneration"]
    P53PROTEIN -->|"implicated_in"| neurodegeneration
    style P53PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found