Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC31A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | SLC31A1 |
| Full Name | Solute Carrier Family 31 Member 1 (Copper Transporter 1) |
| Chromosome | 9q32 |
| Function | is an essential trace element required for the activity of numerous enzymes critical to energy metabolism, antioxidant defense, neurotransmitter synthesis, and iron metabolism. |
| Primary Expression | virtually all tissues, with particularly high expression in: |
| Pathways | Akt |
| UniProt ID | O15431 |
| NCBI Gene ID | 10551 |
| Ensembl ID | ENSG00000137767 |
| OMIM | 603085 |
| GeneCards | SLC31A1 |
| Human Protein Atlas | SLC31A1 |
| Associated Diseases | neurodegeneration |
| Interactions | PER2, HSP70, CLOCK, ATF3, DLAT, AKT |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SLC31A1["<b>SLC31A1</b>"]
Carcinoma{"Carcinoma"}
SLC31A1 -->|"activates"| Carcinoma
Ms{"Ms"}
SLC31A1 -->|"activates"| Ms
Tumor{"Tumor"}
SLC31A1 -->|"activates"| Tumor
PER2["PER2"]
SLC31A1 -->|"activates"| PER2
HSP70["HSP70"]
SLC31A1 -->|"activates"| HSP70
CLOCK["CLOCK"]
SLC31A1 -->|"activates"| CLOCK
ATF3["ATF3"]
SLC31A1 -->|"activates"| ATF3
DLAT["DLAT"]
SLC31A1 -->|"activates"| DLAT
Akt(["Akt"])
SLC31A1 -->|"activates"| Akt
neurodegeneration["neurodegeneration"]
SLC31A1 -->|"implicated in"| neurodegeneration
AKT["AKT"]
AKT -->|"activates"| SLC31A1
style SLC31A1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Source | Relation | Type | Str |
|---|---|---|---|
| AKT | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||