concept

V-ATPASE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about V-ATPASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

26Connections
0Hypotheses
0Analyses
4Outgoing
3Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameV-ATPASE
Key Genes/ProteinsATG16L1, RAB7, MAPT, SOPF, VGLUT1

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

CLCN10 — Chloride Voltage-Gated Channel 10

gene · 4939 words

Autophagy Mechanisms

mechanism · 4866 words

APOC4 — Apolipoprotein C-IV

gene · 4687 words

Mitophagy Pathway in Neurodegeneration

mechanism · 4637 words

Pathway Diagram

graph TD
    V_ATPASE["V-ATPASE"]
    V_ATPASE -->|"regulates"| LC3_Associated_Phagocytosis["LC3-Associated Phagocytosis"]
    V_ATPASE -->|"regulates"| Rab7["Rab7"]
    V_ATPASE -->|"regulates"| Late_Endosomal_Ph["Late Endosomal Ph"]
    V_ATPASE -->|"interacts"| ATG16L1["ATG16L1"]
    V_ATPASE -->|"activates"| Casm["Casm"]
    V_ATPASE -->|"activates"| xenophagy["xenophagy"]
    V_ATPASE -->|"activates"| Rab7a["Rab7a"]
    SOPF["SOPF"] -->|"inhibits"| V_ATPASE
    ATP6V1G1["ATP6V1G1"] -->|"expressed in"| V_ATPASE
    VGLUT1["VGLUT1"] -->|"depends_on"| V_ATPASE
    ATG16L1_WD40_domain["ATG16L1 WD40 domain"] -->|"interacts"| V_ATPASE
    Rab7 -->|"interacts"| V_ATPASE
    NADPH_oxidase["NADPH oxidase"] -->|"interacts"| V_ATPASE
    Salmonella_SopF["Salmonella SopF"] -->|"inhibits"| V_ATPASE
    TMEM55B["TMEM55B"] -->|"contributes to"| V_ATPASE

Outgoing (13)

TargetRelationTypeStr
LC3-Associated Phagocytosisregulatesprocess0.95
ATG16L1interacts_withprotein0.93
Casmactivatesprocess0.92
RAB7activatesprotein0.90

Incoming (13)

SourceRelationTypeStr
MAPTbindsgene0.90
SOPFinhibitsprotein0.88
VGLUT1depends_onprotein0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found