Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about V-ATPASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
V_ATPASE["V-ATPASE"]
V_ATPASE -->|"regulates"| LC3_Associated_Phagocytosis["LC3-Associated Phagocytosis"]
V_ATPASE -->|"regulates"| Rab7["Rab7"]
V_ATPASE -->|"regulates"| Late_Endosomal_Ph["Late Endosomal Ph"]
V_ATPASE -->|"interacts"| ATG16L1["ATG16L1"]
V_ATPASE -->|"activates"| Casm["Casm"]
V_ATPASE -->|"activates"| xenophagy["xenophagy"]
V_ATPASE -->|"activates"| Rab7a["Rab7a"]
SOPF["SOPF"] -->|"inhibits"| V_ATPASE
ATP6V1G1["ATP6V1G1"] -->|"expressed in"| V_ATPASE
VGLUT1["VGLUT1"] -->|"depends_on"| V_ATPASE
ATG16L1_WD40_domain["ATG16L1 WD40 domain"] -->|"interacts"| V_ATPASE
Rab7 -->|"interacts"| V_ATPASE
NADPH_oxidase["NADPH oxidase"] -->|"interacts"| V_ATPASE
Salmonella_SopF["Salmonella SopF"] -->|"inhibits"| V_ATPASE
TMEM55B["TMEM55B"] -->|"contributes to"| V_ATPASE| Target | Relation | Type | Str |
|---|---|---|---|
| LC3-Associated Phagocytosis | regulates | process | 0.95 |
| ATG16L1 | interacts_with | protein | 0.93 |
| Casm | activates | process | 0.92 |
| RAB7 | activates | protein | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||