concept

WNT SIGNALING PATHWAY

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT SIGNALING PATHWAY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections
0Hypotheses
0Analyses
7Outgoing
16Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameWNT SIGNALING PATHWAY

Wiki Pages (20)

Knowledge base pages for this entity

GSK-3β in Neurodegeneration

mechanism · 5020 words

Wnt Non-Canonical Signaling Pathways in Neurodegeneration

mechanism · 4664 words

NF-kB Signaling Pathway in Neurodegeneration

mechanism · 3782 words

Neurogenesis

cell · 3757 words

Neurogenesis and Neurodegeneration

mechanism · 3443 words

Pathway Diagram

graph TD
    WNT_SIGNALING_PATHWAY["WNT SIGNALING PATHWAY"]
    WNT_SIGNALING_PATHWAY -->|"activates"| HIF_1_["HIF-1alpha"]
    WNT_SIGNALING_PATHWAY -->|"regulates"| MYC["MYC"]
    WNT_SIGNALING_PATHWAY -->|"contributes to"| High_Risk_Ovarian_Cancer["High-Risk Ovarian Cancer"]
    WNT_SIGNALING_PATHWAY -->|"regulates"| Ischemia_reperfusion_injury["Ischemia-reperfusion injury"]
    WNT_SIGNALING_PATHWAY -->|"regulates"| tissue_damage["tissue damage"]
    WIF1["WIF1"] -->|"inhibits"| WNT_SIGNALING_PATHWAY
    NPC1["NPC1"] -->|"regulates"| WNT_SIGNALING_PATHWAY
    Cluster_1_Upregulated_Genes["Cluster 1 Upregulated Genes"] -->|"involved_in"| WNT_SIGNALING_PATHWAY
    Cluster_1_Upregulated_DEGs["Cluster 1 Upregulated DEGs"] -->|"upregulates"| WNT_SIGNALING_PATHWAY
    EPHA5["EPHA5"] -->|"activates"| WNT_SIGNALING_PATHWAY
    BAX["BAX"] -->|"regulates"| WNT_SIGNALING_PATHWAY
    BCL2["BCL2"] -->|"regulates"| WNT_SIGNALING_PATHWAY
    DKK1["DKK1"] -->|"inhibits"| WNT_SIGNALING_PATHWAY

Outgoing (7)

TargetRelationTypeStr
HIF-1αactivatesprotein0.90
AUTOPHAGYregulatesprocess0.90
MYCregulatesgene0.85
Ovarian Cancercontributes_todisease0.85
High-Risk Ovarian Cancercontributes_tophenotype0.78

Incoming (16)

SourceRelationTypeStr
WIF1inhibitsprotein0.95
Thermal Adaptationinhibitsprocess0.95
NPC1regulatesgene0.90
Cluster 1 Upregulated Genesinvolved_inbiomarker0.88
Cluster 1 Upregulated DEGsupregulatesbiomarker0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found