concept

LIVER FIBROSIS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LIVER FIBROSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

48Connections

0Hypotheses

0Analyses

0Outgoing

48Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LIVER FIBROSIS

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    LIVER_FIBROSIS["LIVER FIBROSIS"]
    FOXO1["FOXO1"] -.protects against.-> LIVER_FIBROSIS
    CCL4["CCL4"] -->|"causes"| LIVER_FIBROSIS
    Hepatocyte_FoxO1_Deficiency["Hepatocyte FoxO1 Deficiency"] -.protects against.-> LIVER_FIBROSIS
    NINJ2["NINJ2"] -->|"contributes to"| LIVER_FIBROSIS
    MASP1["MASP1"] -->|"promotes"| LIVER_FIBROSIS
    Carbon_Tetrachloride["Carbon Tetrachloride"] -->|"causes"| LIVER_FIBROSIS
    PIEZO1["PIEZO1"] -.protects against.-> LIVER_FIBROSIS

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (48)

Source	Relation	Type	Str
FOXO1	protects_against	gene	0.95
Hepatocyte FoxO1 Deficiency	protects_against	phenotype	0.95
MASP1	promotes	protein	0.95
Carbon Tetrachloride	causes	compound	0.95
NINJ2	contributes_to	gene	0.95
PIEZO1	protects_against	protein	0.92
PIEZO1	therapeutic_target	gene	0.92
PIEZO1	treats	gene	0.90
HSC Activation	contributes_to	process	0.90
Hepatic Stellate Cell Activation	contributes_to	process	0.90
HK2 Deletion	inhibits	process	0.90
SLC7A11	protects_against	gene	0.90
PIEZO1	associated_with	gene	0.90
Hepatic Stellate Cell Ferroptosis	associated_with	process	0.90
Sorafenib	treats	drug	0.90
FOXO1	regulates	gene	0.90
LRG1	promotes	protein	0.90
PIEZO1	involved_in	gene	0.90
Hepatic Stellate Cell Activation	causes	process	0.90
TGFB1	contributes_to	gene	0.90
Liver Inflammation	associated_with	process	0.90
Hepatic Stellate Cells	drives	cell_type	0.90
PIEZO1	suppresses	gene	0.90
excessive inflammation	causes	process	0.90
Inflammation	associated_with	process	0.90
MAPK	associated_with	pathway	0.90
esculin	treats	drug	0.88
Hepatic Stellate Cell	involved_in	cell_type	0.88
inflammation resolution	suppresses	process	0.87
Hepatic Inflammation	associated_with	disease	0.85
Hepatic Stellate Cells	contributes_to	cell_type	0.85
Hepatic Stellate Cells	involved_in	cell_type	0.85
FUNDC1	contributes_to	protein	0.85
Primary Biliary Cholangitis	causes	disease	0.85
IL-1Β	contributes_to	protein	0.85
NRF2	protects_against	protein	0.82
TNC	associated_with	protein	0.80
ACBA	treats	drug	0.80
SLC7A11	inhibits	gene	0.80
FOXO1	prevents	gene	0.80
FUNDC1	implicated_in	gene	0.80
Piezo1	inhibits	gene	0.80
FERROPTOSIS	causes	process	0.80
LRG1	biomarker_for	protein	0.75
FUNDC1	biomarker_for	gene	0.75
aloe-emodin	treats	drug	0.70
STAT3	associated_with	protein	0.70
TNF	promotes	protein	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found