concept

LYSOSOMES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LYSOSOMES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections
0Hypotheses
0Analyses
20Outgoing
1Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameLYSOSOMES
Key Genes/ProteinsC9ORF72

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

therapeutic · 15567 words

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

Novel Therapy Index

idea · 10647 words

Pathway Diagram

graph TD
    LYSOSOMES["LYSOSOMES"]
    LYSOSOMES -->|"regulates"| Autophagy["Autophagy"]
    LYSOSOMES -->|"involved_in"| Endocytosis["Endocytosis"]
    LYSOSOMES -->|"involved_in"| Lysosomal_Storage_Disorders["Lysosomal Storage Disorders"]
    LYSOSOMES -->|"causes"| Lysosomal_Storage_Diseases["Lysosomal Storage Diseases"]
    LYSOSOMES -->|"causes"| Neurodegeneration["Neurodegeneration"]
    LYSOSOMES -->|"involved_in"| Amyloid_Beta["Amyloid Beta"]
    LYSOSOMES -->|"involved_in"| Nutrient_Sensing["Nutrient Sensing"]
    TMEM192["TMEM192"] -->|"expressed in"| LYSOSOMES
    Autophagy -->|"involved_in"| LYSOSOMES
    Endocytosis -->|"involved_in"| LYSOSOMES
    Lysosome_Quality_Control["Lysosome Quality Control"] -->|"regulates"| LYSOSOMES
    Autophagosomes["Autophagosomes"] -->|"interacts"| LYSOSOMES
    Phosphatidylinositol_3_Phospha["Phosphatidylinositol 3-Phosphate"] -->|"regulates"| LYSOSOMES
    Lysosome_Membrane_Protein_Regu["Lysosome Membrane Protein Regulation"] -->|"regulates"| LYSOSOMES
    Lysosome_Membrane_Protein_Degr["Lysosome Membrane Protein Degradation"] -->|"involved_in"| LYSOSOMES

Outgoing (20)

TargetRelationTypeStr
Autophagyregulatesprocess0.95
Endocytosisinvolved_inprocess0.95
Autophagyinvolved_inprocess0.95
Lysosomal Storage Disordersinvolved_indisease0.90
Hematoma clearanceinvolved_inprocess0.90

Incoming (22)

SourceRelationTypeStr
C9ORF72regulatesgene0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found