Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MIDDLE_TEMPORAL_GYRUS_SPINY_L5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | "MIDDLE TEMPORAL GYRUS"_SPINY_L5 |
graph TD
_MIDDLE_TEMPORAL_GYRUS__SPINY_["'MIDDLE TEMPORAL GYRUS'_SPINY_L5"]
TREM2["TREM2"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
APOE["APOE"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
LRP1["LRP1"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
BDNF["BDNF"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
SNCA["SNCA"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
MAPT["MAPT"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
APP["APP"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_
PARP1["PARP1"] -->|"expressed in"| _MIDDLE_TEMPORAL_GYRUS__SPINY_| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TREM2 | expressed_in | gene | 0.70 |
| APOE | expressed_in | gene | 0.70 |
| LRP1 | expressed_in | gene | 0.70 |
| BDNF | expressed_in | gene | 0.70 |
| SNCA | expressed_in | gene | 0.70 |
| MAPT | expressed_in | gene | 0.70 |
| APP | expressed_in | gene | 0.70 |
| PARP1 | expressed_in | gene | 0.70 |
| NLRP3 | expressed_in | gene | 0.70 |
| GBA1 | expressed_in | gene | 0.70 |
| LRRK2 | expressed_in | gene | 0.70 |
| C1QA | expressed_in | gene | 0.70 |
| P2RY12 | expressed_in | gene | 0.70 |
| AQP4 | expressed_in | gene | 0.70 |
| SMPD1 | expressed_in | gene | 0.70 |
| CYP46A1 | expressed_in | gene | 0.70 |
| SLC16A1 | expressed_in | gene | 0.70 |
| TET2 | expressed_in | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-02 | 5 hypotheses Top: 0.761
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity