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CSGA

CSGA Protein

Score: 0.521 Price: $0.45 Medium Druggability Status: active
HYPOTHESES
1
PAPERS
11
KG EDGES
0
DEBATES
0

Druggability & Clinical Context

Druggability
Medium
Score: 0.50
Clinical Stage
Phase I
Target Class
Protein
Safety
0.50
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.50
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Targeting Bacterial Curli Fibrils to Prevent α-Synuclein Cross-Seeding
Known Drugs:
No known drugs targeting this protein
Structural Data:

Linked Hypotheses (1)

Targeting Bacterial Curli Fibrils to Prevent α-Synuclein Cross-Seeding0.488

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.50 (20%) Evidence 0.79 (20%) Safety 0.50 (15%) Competitive 0.90 (10%) Connectivity 0.00 (10%) 0.521 composite

Knowledge Graph (20)

activates (1)

CSGA → APP

associated with (4)

CSGA → neurodegeneration
CSGA → Rb
CSGA → Alzheimer
CSGA → Als

co associated with (3)

CSGA → TLR4
CSGA → GPR109A
CSGA → TDC

debate co mention (4)

CSGA → GPR109A
CSGA → neuroinflammation
CSGA → TDC
CSGA → DDC

implicated in (5)

CSGA → ms
CSGA → parkinson
CSGA → als
CSGA → alzheimer
CSGA → neurodegeneration

interacts with (1)

CSGA → Rb

regulates (2)

CSGA → Als
CSGA → Parkinson

Debate History (0)

No debates yet

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