gene 839 words KG: APOC2 2026-03-22
kind:genesection:genesstate:published
Contents

APOC2 Gene

🧬 Gene Info
Gene SymbolAPOC2
Chromosome19q13.32
FunctionLPL Activation: APOC2 is the essential cofactor for lipoprotein lipase
Primary Expressionthe liver and small intestine
Molecular Weight8.8 kDa
Amino Acids79 aa
Exons4
PathwaysCholesterol
Ensembl IDENSG00000134901
GeneCardsAPOC2
Human Protein AtlasAPOC2
Nutritional statusIncreased by high-carbohydrate diets
InsulinSuppresses APOC2 expression
PPAR agonistsFibrates modulate APOC2 levels
Inflammatory cytokinesTNF-α and IL-6 reduce expression
Associated DiseasesAging, Als, Alzheimer, Dementia, Ms, hypertriglyceridemia
InteractionsSOAT1, ABCA2, LDLR, APOC3, APOE, CYP46A1
KG Connections116 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

APOC2 associated_with MCC
APOC2 associated_with CAT
APOC2 associated_with APOA1
APOC2 causes hypertriglyceridemia
APOC2 activates JAK-STAT signaling pathway
APOC2 associated_with LZTS1
APOC2 associated_with COL4A1
APOC2 activates SOAT1
APOC2 activates ABCA2
APOC2 regulates PSEN2