gene

apoc1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about apoc1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

126Connections

0Hypotheses

0Analyses

8Outgoing

4Incoming

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	APOC1
Full Name	Apolipoprotein C-I
Chromosome	19
Molecular Weight	~9 kDa
Amino Acids	79 aa
Exons	4
Pathways	Interaction
UniProt ID	P02654
NCBI Gene ID	341
Ensembl ID	ENSG00000130208
OMIM	107710
GeneCards	APOC1
Human Protein Atlas	APOC1
Associated Diseases	neurodegeneration
Interactions	apoc2, apoc3, LRP1, CYP46A1, LDLR, LRP8
KG Connections	12 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: apoc1 — AlphaFold P02654 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (9)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    APOC1["APOC1"]
    APOC1 -->|"regulates"| Alzheimer["Alzheimer"]
    APOC1 -->|"regulates"| Als["Als"]
    APOC1 -->|"regulates"| Atherosclerosis["Atherosclerosis"]
    APOC1 -->|"transports"| ALS["ALS"]
    CH25H["CH25H"] -->|"activates"| APOC1
    LRP8["LRP8"] -->|"activates"| APOC1
    APOA1["APOA1"] -->|"activates"| APOC1
    MAPT["MAPT"] -->|"regulates"| APOC1
    LRP1["LRP1"] -->|"activates"| APOC1
    LIPA["LIPA"] -->|"regulates"| APOC1
    ALZHEIMER["ALZHEIMER"] -->|"regulates"| APOC1
    APP["APP"] -->|"regulates"| APOC1

Outgoing (71)

Target	Relation	Type	Str
apoc2	activates	gene	0.50
apoc3	activates	gene	0.50
LRP1	activates	gene	0.50
CYP46A1	activates	gene	0.50
LDLR	activates	gene	0.50
LRP8	activates	gene	0.50
Cholesterol	activates	pathway	0.50
SOAT1	activates	concept	0.50

Incoming (55)

Source	Relation	Type	Str
APOE	activates	gene	0.50
ABCA1	activates	gene	0.50
abca2	activates	gene	0.50
APOA1	activates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

apoc1

Understanding Entity Pages

Wiki Pages (9)

APOC4 — Apolipoprotein C-IV

APOC1 Gene — Apolipoprotein C-I

Apolipoprotein C-III Protein

TREM2 Protein — Triggering Receptor Expressed on Myeloid Cells 2

amyloid-responsive-microglia

APOC2 Gene

Apolipoprotein C-I