| Gene Symbol | ATP7A |
| Full Name | Copper-Transport ATPase |
| Chromosome | Xq21.1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | most tissues except the liver, making it the primary copper transporter for extrahepatic copper metabolism |
| Molecular Weight | 163 kDa |
| Amino Acids | 1500 aa |
| UniProt ID | [Q9Y5K9](https://www.uniprot.org/uniprot/Q9Y5K9) |
| Ensembl ID | ENSG00000136939 |
| OMIM | 300011 |
| GeneCards | ATP7A |
| Human Protein Atlas | ATP7A |
| 8 Transmembrane Helices | Form the copper translocation pore |
| Copper Binding Sites | 6 N-terminal CXXC motifs for copper binding |
| Gate Region | Regulates access to the transport channel |
| Associated Diseases | developmental delay, Menkes disease, neurodegeneration |
| Interactions | Aβ, CP, FDX1, P53, VCP |
| KG Connections | 50 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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