gene 891 words KG: AXIN2
Contents

AXIN2 Gene

🧬 Gene Info
Gene SymbolAXIN2
Chromosome17q24.1
Protein TypeGene
Functionis a critical negative regulator of the Wnt/beta-catenin signaling pathway.
Primary Expressionneural stem cells (NSCs) in the adult subventricular zone (SVZ) and dentate gyrus subgranular zone (SGZ):
Molecular Weight88 kDa
Amino Acids778 aa
PathwaysWnt, Wnt signaling, Wnt pathway
UniProt IDQ9Y2T1
NCBI Gene ID8313
Ensembl IDENSG00000168646
GeneCardsAXIN2
Human Protein AtlasAXIN2
Associated DiseasesCancer, Carcinoma
Known Drugs/Compoundsrapamycin
InteractionsAMPK, ATG, BECN1, CCND1, CYCLIN D1, FAM83A
KG Connections237 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TCF4 associated_with AXIN2
MYC associated_with AXIN2
LC3 associated_with AXIN2
MTOR associated_with AXIN2
BECN1 associated_with AXIN2
CTNNB1 associated_with AXIN2
AXIN2 associated_with GAPDH
AXIN2 associated_with SQSTM1
AXIN2 associated_with RAB7A
AXIN2 associated_with LAMP1

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