| Gene Symbol | PINK1 |
| Full Name | Deficient Dopaminergic Neurons in Parkinson's Disease |
| Chromosome | 1p36.12 |
| Protein Family | Serine/threonine kinase family |
| Protein Type | Kinase |
| Function | is a mitochondrial serine/threonine-protein kinase encoded by the PINK1 gene [@zheng2021]. |
| Primary Expression | Mitochondrial outer membrane |
| Subcellular Localization | mitochondria in neurons. [@valente2004] |
| Molecular Weight | 63 kDa |
| Pathways | Amyloid, Apoptosis, Autophagy, Chaperone, Cholesterol |
| UniProt ID | Q9BXM7 |
| NCBI Gene ID | 65018 |
| Ensembl ID | ENSG00000158828 |
| OMIM | 608309 |
| GeneCards | PINK1 |
| Human Protein Atlas | PINK1 |
| Associated Diseases | AD, ALI, ALS, APOPTOSIS, Aging |
| Known Drugs/Compounds | DEFERIPRONE, RAPAMYCIN, MELATONIN, propionic acid, Ligustilide, BGP-15 |
| Interactions | BCL2L13, NLRP3, ABCD3, FIP200, RTN3, SESN2 |
| KG Connections | 3597 knowledge graph edges |
| Databases | GeneCardsHPASTRING |