gene 792 words KG: TYROBP 2026-03-24
kind:genesection:genesstate:published
Contents

TYROBP — TYRO Binding Protein (DAP12)

🧬 Gene Info
Gene SymbolTYROBP
Full NameTYRO Binding Protein (DAP12)
AliasesDAP12
Chromosome19q13.12
Protein TypeAdaptor Protein
Functionis a transmembrane signaling adaptor protein that plays critical roles in innate immunity and microglial function in the central nervous system.
Primary ExpressionMicroglia, Monocytes, NK cells, Osteoclasts
Molecular Weight12.1 kDa
Amino Acids113 aa
PathwaysInnate Immunity
UniProt IDQ9Y241
NCBI Gene ID7305
Ensembl IDENSG00000111653
OMIM605712
GeneCardsTYROBP
Human Protein AtlasTYROBP
Associated DiseasesALS, ALZHEIMER'S DISEASE, Aging, Alzheimer
Known Drugs/CompoundsBERBERINE
InteractionsRANK, OVERVIEW, TREM2, DAP12, APOE, SPI1
KG Connections383 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph