gene 1,686 words KG: DLAT
Contents

DLAT Gene

🧬 Gene Info
Gene SymbolDLAT
Full NameDihydrolipoamide S-Acetyltransferase
Chromosome11q23.1
FunctionDLAT is the central structural and catalytic component of the pyruvate dehydrogenase complex, forming a 24-mer cubic core that organizes the entire complex[@patel2014]
PathwaysAkt, Apoptosis, Immune Response, Pi3K/Akt, apoptosis
UniProt ID[P10515](https://www.uniprot.org/uniprot/P10515)
Ensembl IDENSG00000150768
OMIM608770
GeneCardsDLAT
Human Protein AtlasDLAT
Lipoic acid synthesisDe novo creation of the dithiolane ring
Associated DiseasesAlzheimer's disease
InteractionsAKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AND, APOPTOSIS
KG Connections69 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

AKT activates DLAT
SLC31A1 activates DLAT
PER2 activates DLAT
HSP70 activates DLAT
CLOCK activates DLAT
ATF3 activates DLAT
DLAT associated_with copper
DLAT regulates CaMKII
DLAT activates JAK2
DLAT activates STAT5A

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