| Gene Symbol | ACVR2A |
| Full Name | Activin A Receptor Type 2A |
| Chromosome | 2q22.3 |
| Protein Type | Serine/Threonine Kinase |
| Function | is a member of the TGF-beta superfamily of serine/threonine kinase receptors. |
| Amino Acids | 513 aa |
| Pathways | Apoptosis, Dna Repair, Epigenetic |
| UniProt ID | [P27037](https://www.uniprot.org/uniprot/P27037) |
| Ensembl ID | ENSG00000198893 |
| GeneCards | ACVR2A |
| Human Protein Atlas | ACVR2A |
| Inhibins | Can form complexes with ACVR2A to modulate signaling |
| BMPs | Bone morphogenetic proteins can also activate ACVR2A at higher concentrations |
| Phosphorylation | Multiple serine/threonine residues in the kinase domain are phosphorylated during activation |
| Glycosylation | N-linked glycosylation in the extracellular domain affects ligand binding |
| Associated Diseases | Als, Cancer, Colorectal Cancer, Gastric Cancer, HCC, Hepatocellular Carcinoma |
| Interactions | CTNNB1, TP53, TERT, GENES, CANCER, OXIDATIVE STRESS |
| KG Connections | 66 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |