gene 1,409 words KG: ADRB2 2026-03-27
kind:genesection:genestopic:parkinsonstopic:alzheimers
Contents

ADRB2 Gene

🧬 Gene Info
Gene SymbolADRB2
Full NameBeta-2 Adrenergic Receptor
Chromosome5q31-q32
Functionencodes a 413-amino acid protein.
Amino Acids4477 aa
Exons4
UniProt IDP07550
NCBI Gene ID154
Ensembl IDENSG00000169252
OMIM109630
GeneCardsADRB2
Human Protein AtlasADRB2
TATA boxCore promoter element
CRE elementscAMP response elements for regulated expression
AP-1 sitesResponsive to growth factors and cytokines
Associated DiseasesALS, Alzheimer, Alzheimer'S Disease, Anxiety, Dementia
InteractionsGSK3B, LYN, MUL1, PSEN1, Rb, APP
KG Connections149 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (14)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: activates
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with
ATG5 — Autophagy Related 5
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

ADRB2 associated_with GSTP1
ADRB2 associated_with ABCB1
ADRB2 associated_with COMT
ADRB2 associated_with CHAT
ADRB2 associated_with HMGCR
ADRB2 associated_with ABCG2
ADRB2 associated_with OPRM1
ADRB2 associated_with MAOB
ADRB2 associated_with CYP3A4
ADRB2 associated_with SLC6A3