gene 1,955 words KG: CASS2 2026-03-28
kind:genesection:genesstate:published
Contents

CASS2 — CASP2 and RIPK1 Domain Containing Adaptor

🧬 Gene Info
Gene SymbolCASS2
Full NameCASP2 and RIPK1 Domain Containing Adaptor
AliasesCRADD
Chromosome10p15.1
Functionencodes a protein of 312 amino acids with a molecular weight of approximately 35 kDa.
Molecular Weight35 kDa
Amino Acids312 aa
Ensembl IDENSG00000103811
GeneCardsCASS2
Human Protein AtlasCASS2
Associated DiseasesAlzheimer, Autoimmune, Cancer
InteractionsCASS4
KG Connections16 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Alzheimer Indonesia
institution · KG edge: associated_with
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: associated_with
SRC Gene
gene · KG edge: associated_with
FYN — FYN Proto-Oncogene, Src Family Tyrosine Kinase
gene · KG edge: associated_with
CASS4 — Cas Scaffold Protein Family Member 4
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CASS2 interacts_with CASS4
CASS2 co_expressed_with CASS4
CASS2 co_expressed_with SRC
CASS2 associated_with Alzheimer
CASS2 associated_with Cancer
CASS2 associated_with Autoimmune
CASS2 associated_with Cell Cycle
AURKA associated_with CASS2
SRC associated_with CASS2
CASS4 associated_with CASS2