gene 800 words KG: SRC
Contents

SRC Gene

🧬 Gene Info
Gene SymbolSRC
Protein TypeReceptor
FunctionSRC encodes a member of the Src family of non-receptor tyrosine kinases (SFKs).
PathwaysApoptosis, Autophagy, Complement, Dendritic Spine, Differentiation
Ensembl IDENSG00000197122
GeneCardsSRC
Human Protein AtlasSRC
Associated DiseasesAD, ALI, Als, Alzheimer, Autism
Known Drugs/CompoundsDEP, DOP
InteractionsABL1, ACE, ACSL4, AD, ADRB2, AGING
KG Connections1076 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (22)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.89
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Phase-Separated Organelle Targeting
Score: 0.73
Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Stress Granule Phase Separation Modulators
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.70
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
Extracellular Matrix Stiffness Modulation
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
RNA Granule Nucleation Site Modulation
Score: 0.66
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
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Related Analyses (4)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Functional analysis of EFNB1-EPHB4 interaction in EMT
exploratory · proposed · Score: 0.80

See Also (8)

ACE Gene
gene · KG edge: inhibits
ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: activates
ADRB2 Gene
gene · KG edge: interacts_with
AKT1 Gene
gene · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: activates

Knowledge Graph (12 edges)

IL6 activates SRC
SRC activates EMT
PIEZO1 activates SRC
SRC activates p38
JUN regulates SRC
TP53 interacts_with SRC
EFNB1 interacts_with SRC
EPHB4 interacts_with SRC
FASN activates SRC
SRC activates HK1

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